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Abstract
This tool provides a graphical user interface to create, run, and visualize a multicellular model using PhysiCell. The default model is the PhysiCell "template" model which defines a single cell type having a relatively simple phenotype: 1) a cell cycle that results in proliferation and 2) cell death. In the Run tab, click the "Run simulation" button and, once it begins, in the Plot tab, click "Play" to see results. To terminate the simulation before it completes, click the "Cancel" button in the Run tab.
In the Model menu, select either the "biorobots" or "tumor immune" model. Run and Plot them to investigate. See the Rules tab for the "tumor_immune" model to see several rules defined using signals and behaviors.
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A. Ghaffarizadeh, R. Heiland, S.H. Friedman, S.M. Mumenthaler, and P. Macklin. PhysiCell: an open source physics-based cell simulator for 3-D multicellular systems. PLoS Comput. Biol. 14(2):e1005991, 2018. DOI: 10.1371/journal.pcbi.1005991.