Soft Electronic and Microfluidic Systems for the Skin

By John A. Rogers

Materials Science and Engineering, Northwestern University, Evanston, IL

Published on

Abstract

Biological systems are mechanically soft, with complex, 3D curvilinear shapes; modern electronic technologies are rigid, with simple, 2D layouts. Technologies that eliminate this profound mismatch in physical properties create opportunities for devices that can intimately integrate with the body, for diagnostic, therapeutic or surgical function with important, unique capabilities in biomedical research and clinical healthcare. Over the last decade, a convergence of new concepts in materials science, physics, electrical engineering and advanced manufacturing has led to the emergence of diverse, novel classes of 'biocompatible' electronic platforms. This talk describes the key ideas, and presents some of the most recent device examples, including wireless, skin-like electronic 'tattoos' for continuous monitoring of vital signs in neonatal intensive care, microfluidic/electronic platforms that can capture, store and perform biomarker analysis on sweat, and 3D open-mesh electronic mesostructures for active cellular scaffolds.

Bio

John A. Rogers Professor John A. Rogers obtained BA and BS degrees in chemistry and in physics from the University of Texas, Austin, in 1989. From MIT, he received SM degrees in physics and in chemistry in 1992 and the PhD degree in physical chemistry in 1995. From 1995 to 1997, Rogers was a Junior Fellow in the Harvard University Society of Fellows. During this time he also served as a founder and Director of Active Impulse Systems, a company that commercialized technologies developed during his PhD work. He joined Bell Laboratories as a Member of Technical Staff in the Condensed Matter Physics Research Department in 1997, and served as Director of this department from the end of 2000 to the end of 2002.

From 2003-2016, he was on the faculty at University of Illinois at Urbana/Champaign, where he held a Swanlund Chair, the highest chaired position at the university, with a primary appointment in the Department of Materials Science and Engineering, and joint appointments in the Departments of Chemistry, Bioengineering, Mechanical Science and Engineering, and Electrical and Computer Engineering. He served as the Director of a Nanoscale Science and Engineering Center on nanomanufacturing, funded by the National Science Foundation, from 2009-2012 and as Director of the Seitz Materials Research Laboratory from 2012 to 2016.

In September of 2016, he joined Northwestern University as the Louis Simpson and Kimberly Querrey Professor of Materials Science and Engineering, Biomedical Engineering, Mechanical Engineering, Electrical Engineering and Computer Science, Chemistry and Neurological Surgery, where he is also the founding Director of the newly endowed Center on Bio-Integrated Electronics.

Rogers’ research includes fundamental and applied aspects of nano and molecular scale fabrication as well as materials and patterning techniques for unusual electronic and photonic devices, with an emphasis on bio-integrated and bio-inspired systems. He has published more than 650 papers, and is an inventor on over 100 patents and patent applications, more than 70 of which are licensed or in active use by large companies and startups that he has co-founded.

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Cite this work

Researchers should cite this work as follows:

  • John A. Rogers (2019), "Soft Electronic and Microfluidic Systems for the Skin," https://nanohub.org/resources/30614.

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Time

Location

Physics, Room 203, Purdue University, West Lafayette, IN

Tags

Soft Electronic and Microfluidic Systems for the Skin
  • Soft Electronic and Microfluidic Systems for the Skin 1. Soft Electronic and Microfluid… 0
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  • Soft Electronics for the Human Body 2. Soft Electronics for the Human… 149.01568234901569
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  • Materials, Structures In Biological Systems 3. Materials, Structures In Biolo… 287.18718718718719
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  • 3 Emerging Directions in Electronic Mtls Research 4. 3 Emerging Directions in Elect… 341.87520854187522
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  • Candidate Semiconductors for Bio-Integrated Electronics 5. Candidate Semiconductors for B… 406.03937270603939
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  • Silicon wafers 6. Silicon wafers 525.42542542542549
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  • Stretchable Silicon 7. Stretchable Silicon 560.39372706039376
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  • Mechanics in Filamentary Serpentine Networks 8. Mechanics in Filamentary Serpe… 709.10910910910911
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  • Precise, Skin-like Mechanical Properties 9. Precise, Skin-like Mechanical … 810.24357691024363
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  • Deterministic Composites, Precisely Matched to the Skin 10. Deterministic Composites, Prec… 854.88822155488822
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  • Fractal Layouts – Natural and Engineered Systems 11. Fractal Layouts – Natural an… 909.90990990991
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  • Filamentary Fractals – Peano Curve Example 12. Filamentary Fractals – Peano… 978.37837837837844
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  • Constructing Peano Curves 13. Constructing Peano Curves 1035.935935935936
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  • Mechanics Modeling of Stretching of Peano Curves 14. Mechanics Modeling of Stretchi… 1055.0884217550886
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  • Filling Arbitrary 2D Areas with Fractal Serpentines 15. Filling Arbitrary 2D Areas wit… 1096.5632298965634
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  • Untitled: Slide 16 16. Untitled: Slide 16 1111.644978311645
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  • Epidermal Electronics for the Auricle -- EEG 17. Epidermal Electronics for the … 1130.2302302302303
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  • Persistent EEG for BMI 18. Persistent EEG for BMI 1162.1955288621955
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  • 'Epidermal' Electronics 19. 'Epidermal' Electronics 1183.0830830830832
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  • Quantitative Correlation to Clinical Gold Standards 20. Quantitative Correlation to Cl… 1239.4394394394394
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  • Acousto-Mechanic Information Recorded from The Throat 21. Acousto-Mechanic Information R… 1339.7063730397065
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  • Thermal Actuators/Sensors for Blood Flow Measurement 22. Thermal Actuators/Sensors for … 1381.981981981982
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  • Occlusion and Reperfusion 23. Occlusion and Reperfusion 1464.1307974641309
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  • Measurement Capabilities in Epidermal Electronics 24. Measurement Capabilities in Ep… 1509.3760427093762
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  • Neonatal Intensive Care 25. Neonatal Intensive Care 1543.7437437437438
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  • Wireless ECG Data, Comparison to Clinical Standards 26. Wireless ECG Data, Comparison … 1668.0680680680682
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  • Neonates (NICU) Bland Altman Plot (n=37) 29. Neonates (NICU) Bland Altman P… 1930.6306306306308
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  • Vital signs monitoring 30. Vital signs monitoring 1969.4027360694029
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  • Vital signs monitoring 31. Vital signs monitoring 1996.2295628962297
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  • Vital signs monitoring 32. Vital signs monitoring 2005.1384718051386
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  • Vital signs monitoring 33. Vital signs monitoring 2044.8114781448116
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  • Vital signs monitoring 34. Vital signs monitoring 2070.4371037704373
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  • 20,000 Unit Deployment into India, Pakistan, Zambia 35. 20,000 Unit Deployment into In… 2094.0940940940941
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  • Human Studies in Rehabilitation and Healthcare 36. Human Studies in Rehabilitatio… 2110.4104104104103
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  • Wearable tech aids stroke patients 37. Wearable tech aids stroke pati… 2126.7600934267602
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  • Shirley Ryan Abilitylab 38. Shirley Ryan Abilitylab 2156.0894227560893
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  • Shirley Ryan Abilitylab 39. Shirley Ryan Abilitylab 2301.7017017017019
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  • Clinical Studies – Multiple Patients, Simultaneously 40. Clinical Studies – Multiple … 2303.5368702035371
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  • Mechano-Acoustic Sensing from the Suprasternal Notch 41. Mechano-Acoustic Sensing from … 2303.9706373039708
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  • Bio-signal Monitoring via Single Wearable Device 42. Bio-signal Monitoring via Sing… 2304.6379713046381
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  • Epidermal Microfluidic Devices and Sweat Analytics 43. Epidermal Microfluidic Devices… 2305.0717384050718
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  • Epidermal Microfluidic Devices and Sweat Analytics 44. Epidermal Microfluidic Devices… 2399.2325658992327
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  • Soft, Skin-Compatible Mechanics and Adhesives 45. Soft, Skin-Compatible Mechanic… 2459.95995995996
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  • Experimental and Computational Mechanics 46. Experimental and Computational… 2494.6279612946282
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  • Sci. Transl. Med 8, 366ra165 (2016). 47. Sci. Transl. Med 8, 366ra165 (… 2498.1648314981649
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  • Science Translational Medicine 48. Science Translational Medicine 2540.2402402402404
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  • Skin-like Microfluidics as Art – Featured at MoMA 49. Skin-like Microfluidics as Art… 2557.0904237570903
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  • Skin-like Microfluidics as Art – Featured at MoMA 50. Skin-like Microfluidics as Art… 2598.0313646980317
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  • Skin-like Microfluidics as Art – Featured at MoMA 51. Skin-like Microfluidics as Art… 2609.3760427093762
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  • Skin-like Microfluidics as Art – Featured at MoMA 52. Skin-like Microfluidics as Art… 2610.343677010344
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  • Skin-like Microfluidics as Art – Featured at MoMA 53. Skin-like Microfluidics as Art… 2611.8118118118118
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  • Skin-like Microfluidics as Art – Featured at MoMA 54. Skin-like Microfluidics as Art… 2613.5135135135138
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  • Skin-like Microfluidics as Art – Featured at MoMA 55. Skin-like Microfluidics as Art… 2614.748081414748
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  • Multifunctional Devices With Chrono-Sampling 56. Multifunctional Devices With C… 2620.9876543209875
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  • Multifunctional Devices With Chrono-Sampling 57. Multifunctional Devices With C… 2641.1077744411077
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  • Dehydration and Abnormal Sweating in Stroke Patients 58. Dehydration and Abnormal Sweat… 2664.064064064064
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  • Custom Devices for Use with Stroke Patients 59. Custom Devices for Use with St… 2667.9012345679012
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  • Cystic Fibrosis Screening – Clinical Evaluations 60. Cystic Fibrosis Screening – … 2668.6353019686353
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  • Cystic Fibrosis Screening – Clinical Evaluations 61. Cystic Fibrosis Screening – … 2698.8321654988322
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  • Actual sweat stimulation 63 µL 62. Actual sweat stimulation 63 µ… 2725.2585919252588
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  • Untitled: Slide 63 63. Untitled: Slide 63 2730.1968635301969
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  • Field Studies at With NFL Teams (During Practice) 64. Field Studies at With NFL Team… 2734.7681014347681
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  • Major League Baseball (During Games) 65. Major League Baseball (During … 2744.3443443443443
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  • Gatorade 66. Gatorade 2801.0677344010678
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  • Gatorade 67. Gatorade 2844.6112779446112
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  • Hydrocephalus and Shunts 68. Hydrocephalus and Shunts 2845.9459459459463
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  • Hydrocephalus and Shunts 69. Hydrocephalus and Shunts 2930.2969636302969
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  • Pilot Studies on Patients (n=11) 70. Pilot Studies on Patients (n=1… 2949.8498498498498
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  • Patient perspective 71. Patient perspective 2971.2045378712046
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  • The Future of Digital Health is Soft, Stretchy and Skin-Integrated 72. The Future of Digital Health i… 3116.0493827160494
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  • Senior Collaborators 73. Senior Collaborators 3132.0653987320657
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  • Research Team – Northwestern, 6/2018 74. Research Team – Northwestern… 3147.4808141474809
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