This tool can be used to run a simulation with extracellular matrix (ECM) interaction and intracellular signalling using boolean modelling. 

You can select the node of the boolean network you want to monitor, in the configuration tab (for example Cell_Cell, Nei2, Oxy, etc...); the active nodes (node=1) will be coloured in red, while the inactive nodes will be coloured in blue.

You can also choose to visualize the amount of ECM contact by selecting a different color function (0 for ECM contact, 1 for motility percentage, 2 for nodes).

Researchers should cite this work as follows:

• Marco Ruscone, Vincent Noel, Laurence Calzone, Gaelle Letort, Arnau Montagud (2020), "PhysiBoSSa Simulation with ECM," https://nanohub.org/resources/ecmsimul. (DOI: 10.21981/N2E1-QN63).

  BibTex | EndNote

1. Jupyter notebooks
2. PhysiBoSS
3. PhysiBoSSa
4. PhysiCell