How are near-infrared (NIR) dyes used for their enhanced capability in fluorescence detection and imaging, tissue penetration depth and low background with minimal fluorescence from surrounding tissues? This research focuses on Aggregation Induced Emission (AIE) in order to utilize boron difluoride (BF₂) formazanate dyes that can be conjugated with targeting moieties The strategic development of these formazanate dyes offers a unique opportunity to use near-infrared fluorescence imaging techniques to detect and visualize fluorescent probes that are even able to pass through the blood brain barrier in-vivo.

Rice University,  National Science Foundation (NSF) award #EEC-1406885

Researchers should cite this work as follows:

• Jessica Robicheaux, Rice University (2022), "Aggregation Effect of Near-Infrared Boron Difluoride Formazanate Dyes," https://nanohub.org/resources/36311.

  BibTex | EndNote

1. Aggregation Induced Emission (AIE)
2. BORON
3. Boron difluoride
4. fluorescence imaging
5. formazanate dyes
6. Imaging
7. Near-infrared dyes (NIR)