All Categories (1-11 of 11)

1. COVID-19 drug treatments explorer, CompuCell3D

   Tools | 30 Mar 2021 | Contributor(s):: Juliano Ferrari Gianlupi, T.J. Sego

   Explores possible drug treatments for COVID-19; namelly viral entry inhibition and viral replication inhibition

2. PhysiCell simulation of GBM tumour under oHSV1 treatment

   Tools | 28 Mar 2021 | Contributor(s):: Adrianne Jenner, Randy Heiland, Paul Macklin

   Simulation for GBM fragment growth under oHSV1 treatment published in Jenner et al. (2021)

3. Understanding COVID-19 Infection, Immune Response, and Drug Therapy through Multiscale, Multicellular Modeling and Simulation

   Online Presentations | 10 Dec 2020 | Contributor(s):: T.J. Sego

   This workshop presents an open-source Python- and XML-scripted multiscale modeling and simulation framework of an epithelial tissue infected by a virus, a simplified cellular immune response and viral and immune-induced tissue damage and shows how to use it to model basic patterns of infection...

4. Saliva-Based Testing for COVID-19

   Online Presentations | 22 Nov 2020 | Contributor(s):: Mohit Verma

   The Verma lab is developing a molecular test for SARS-CoV-2 that detects the RNA and produces a color change in less than one hour. Using saliva as the sample, this test is easier to use at the point-of-care.

5. Multicellular modeling of SARS-CoV-2 dynamics and virion mediated cell fusion with antiviral drug effects

   Tools | 27 Jul 2020 | Contributor(s):: Yafei Wang, Michael Getz, Randy Heiland, Paul Macklin

   Simulate SARS-CoV-2 dynamics and virion mediated cell fusion under pharmacodynamics effects with PhysiCell

6. A virion infected-cell response tissue simulator

   Tools | 13 Apr 2020 | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin

   Simulate infected cell response to virus with PhysiCell

7. A virion replication tissue simulator

   Tools | 13 Apr 2020 | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin

   Simulate virus replication dynamics with PhysiCell

8. A virion endocytosis tissue simulator

   Tools | 13 Apr 2020 | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin

   Simulate virus endocytosis (internalization), ACE2 receptor dynamics with PhysiCell

9. PhysiCell model for COVID19

   Tools | 26 Mar 2020 | Contributor(s):: Randy Heiland, Yafei Wang, Paul Macklin

   Prototype 2-D multicellular simulation of COVID19.

10. Replication Competent Oncolytic Virus expressing secretable trimeric TRAIL: hypothesis testing

    Tools | 23 Apr 2019 | Contributor(s):: Adrianne Jenner, Paul Macklin

    Using PhysiCell to simulate a replication competent oncolytic virus expressing secretable trimeric TRAIL which induces apoptosis in nearby cells

11. Replication Competent Oncolytic Virus in Epithelial cell layer

    Tools | 18 Apr 2019 | Contributor(s):: Adrianne Jenner, Paul Macklin

    PhysiCell simulation of a replication competent oncolytic virus release from two veins, diffusing through a layer of epithelial cells.