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Abstract
The purpose of this application is to simulate radiation on one primary cancer site and how it affects a secondary tumor site while also using Immunotherapy treatment. This application allows the user to look at how radiation effects cancer cell population, both with and without an immune response, how an Immunotherapy treatment effects cancer cells, as well as how different amounts of radiation and Immunotherapy administered in one treatment effects cancer cell populations. It is important to note that many cancer patients die from a secondary metastatic tumor not from the known primary tumor. By being able to simulate how to eliminate an unknown secondary tumor could help with finding lifesaving radiation and immunotherapy administration strategies.
References
Poleszczuk, Jan, and Heiko Enderling. “The Optimal Radiation Dose to Induce Robust Systemic Anti-Tumor Immunity.” International journal of molecular sciences vol. 19,11 3377. 29 Oct. 2018, doi:10.3390/ijms19113377