Biological matter is often compartmentalized by soft membranes that dynamically change their shape in
response to chemical and mechanical cues. Deformable nanoparticles that mimic this behavior can be used in nanomedicine applications as drug-delivery carriers that can adapt to evolving physiological conditions. In this talk, I will discuss the modeling and simulation of shape-changing nanoparticles. I will describe the nanoHUB tool “Nanoparticle Shape Lab” that enables simulations of the shape deformation of charged nanoparticles for a broad variety of nanoparticle material properties including nanoparticle surface charge, pattern, elasticity and solution conditions such as salinity. The tool enables users to directly interact with the research findings disseminated in several recent publications and extend the exploration to new regions of the material design space.

Engineered nanoBIO Node at Indiana University

Researchers should cite this work as follows:

• Vikram Jadhao (2021), "Shape-changing Nanoparticles for Nanomedicine Applications," https://nanohub.org/resources/34796.

  BibTex | EndNote

1. deformation
2. material properties
3. materials science
4. nano/bio
5. NanoBio Node at Indiana
6. nanoparticles
7. Nanoparticle Shape Lab
8. shape control