All Categories (61-67 of 67)

1. BME 695N Lecture 5: Cell Targeting

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   Online Presentations | 12 Sep 2007 | Contributor(s):: James Leary

   Outline:Overview: targeting nanosystems to cellsAntibody targetingPeptide targetingAptamer targetingAntibodies – polyclonal and monoclonalWhere do antibodies come from – in nature?How do we make them in the laboratory?Monoclonal antibodiesTherapy problems with mouse monoclonal...

2. BME 695N Lecture 4: Designing "Theragnostic" Systems

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   Online Presentations | 04 Sep 2007 | Contributor(s):: James Leary

   Outline:Bridging the gap between diagnostics and therapeuticsHow conventional medicine is practiced in terms of diagnostics and therapeuticsThe consequences of separating diagnostics and therapeuticsA new approach – "theragnostics" (or "theranostics")Examples of current theragnostic...

3. BME 695N Lecture 3: Overview of Basic Nanomedical Systems Design

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   Online Presentations | 29 Aug 2007 | Contributor(s):: James Leary

   Outline:Nanomedical systems – levels of challengesEssential elements of a nanomedical systemRequirements for specific cell targetingConsequences of mis-targetingEngineering around the consequences of mis-targetingSome ways to lower mis-targeting to non-diseased cells

4. BME 695N: Engineering Nanomedical Systems (Fall 2007)

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   Courses | 03 Aug 2007 | Contributor(s):: James Leary

   This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell targeting strategies, choice of core nanomaterials, technologies for testing composition and...

5. BME 695N Lecture 2: Basic Concepts of Nanomedical Systems

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   Online Presentations | 28 Aug 2007 | Contributor(s):: James Leary

   Outline: Features of NanomedicineBottoms up rather than top down approach to medicine Nano-tools on the scale of molecules Cell-by-cell repair approach – regenerative medicine Feedback control system to control drug dosing Elements of good engineering designWhenever possible, use a general design...

6. Re-engineering a Healthy Eye Tissue to Restore Damaged Eyesight

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   Online Presentations | 02 Aug 2007 | Contributor(s):: Margarita Shalaev

   Age-related macular degeneration (AMD) is an eye disease that is the leading cause of blindness in the USA and Western Europe. It affects over one million people in the United States alone. One of the symptoms of AMD is a diseased Bruch’s membrane, which is an important layer in the eye. Our...

7. BME 695N Lecture 1: Need for New Perspectives on Medicine

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   Online Presentations | 03 Aug 2007 | Contributor(s):: James Leary

   Outline:The Progression of MedicineConventional "modern" medicine "Personalized" or "molecular" medicineNanomedicine "single-cell" medicineHow Conventional Medicine Works for Diagnosis of DiseaseIdentification of the "diseased state"Simple measurements of body structure and functionFollow-up...