-
Transforming Pharmaceutical Manufacturing in the 21st Century – Indiana as a Center for Biopharmaceutical Manufacturing
Online Presentations | 21 Jul 2008 | Contributor(s):: Craig K. Svensson
The pharmaceutical industry is moving from a model of fully integrated pharmaceutical companies to fully networked pharmaceutical companies. In this latter model, major pharmaceutical companies are increasingly relying on partnerships for critical elements in the drug development process. This...
-
Quality by Design and Process Analytical Technology for Pharmaceutical Manufacturing in the 21st Century
Online Presentations | 21 Jul 2008 | Contributor(s):: Stephen R. Byrn
PAT or Process Analytical Technology is an initiative and guidance from the U.S. FDA to encourage modernization of pharmaceutical manufacturing. In reality, PAT is a subset of the larger concept of Quality by Design which is the implementation of design concepts for pharmaceutical dosage forms...
-
High-Aspect-Ratio Micromachining of Titanium: Enabling New Functionality and Opportunity in Micromechanical Systems Through Greater Materials Selection
Online Presentations | 18 Jun 2008 | Contributor(s):: Masa Rao
Traditionally, materials selection has been limited in high-aspect-ratio micromechanical applications, due primarily to the predominance of microfabrication processes and infrastructure dedicated to silicon. While silicon has proven to be an excellent material for many of these applications, no...
-
BNC Research Review: The Birck Nanotechnology Center-Progress, Opportunitiees, and Challenges
Online Presentations | 04 Jun 2008 | Contributor(s):: Timothy D. Sands
This presentation is part of a collection of presentations describing the projects, people, and capabilities enhanced by research performed in the Birck Center, and a look at plans for the upcoming year.
-
Three-Dimensional Photonic Crystals
Online Presentations | 11 Feb 2008 | Contributor(s):: Minghao Qi
A photonic crystal (PhCs) is typically a composite of a high-dielectric-constant material (e.g. Si) and a low-constant one (e.g. SiO2 or air), arranged periodically in space. Two dimensional examples include a hexagonal lattice of air holes drilled in a Si slab, or a set of Si rods at square...
-
TCAD Revisited, 2007: An Engineer’s Point of View
Online Presentations | 19 Dec 2007 | Contributor(s):: Constantin Bulucea
This presentation was one of 13 presentations in the one-day forum, "Excellence in Computer Simulation," which brought together a broad set of experts to reflect on the future of computational science and engineering.
-
On the Rise of an Electronic Species: Thoughts on the Impending Singularity
Online Presentations | 29 Nov 2007 | Contributor(s):: Kerry Bernstein
The human brain is vastly more complex that our best supercomputers; yet it can be argued that both systems evolve towards common underlying solutions to fundamental compute problems. Biologically-inspired electronic technologies already are enabling new products, and inversely, nano-electronics...
-
BME 695N Lecture 20: GMP and issues of quality control manufacture of nanodelivery systems
Online Presentations | 15 Nov 2007 | Contributor(s):: James Leary
Outline:Overview What does cGMP mean? Why GMP? Controlling processes means more predictable outcomes… Enforcement What can be learned from the semi-conductor industry clean-room and manufacturing? What doesn’t fit this paradigm?cGMP-level manufacturing Predictable methods lead to predictable...
-
Introduction of MEMS Activity at Nano/Micro System Engineering Lab., Kyoto University
Online Presentations | 15 Sep 2007 | Contributor(s):: OSAMU TABATA
We are aiming at the realization of microsystems and nanosystems with novel and unique functions by integrating functional elements in different domains such as mechanics, electronics, chemistry, optics and biotechnology. These micro/nano systems are expected to be novel machines, which will...
-
Micro-scaled Biochips with Optically Active Surfaces for Near and Far-field Analysis of Cellular Fluorescence
Online Presentations | 31 Aug 2007 | Contributor(s):: Huw Summers
The integration of thin (< 100 nm) metal films with micro-scaleoptical waveguides provides a route to controlled spatialexcitation of cellular fluorescence within a biochip platform.Surface bound electron-plasma oscillations (surface plasmon waves)interact with photons to produce an evanescent...
-
Nanotechnology: Considerations for Facility Design
Online Presentations | 21 May 2007 | Contributor(s):: John Weaver
The growing area of study broadly termed nanotechnology provides a new set of challenges to the facility designer. While evolutionary changes in the quality of clean spaces occur, it is the collaborative nature of this field that requires revolutionary changes in facility design. The main...
-
Nanoscale Antenna Apertures
Online Presentations | 24 Apr 2007 | Contributor(s):: Xianfan Xu
This presentation will discuss light concentration and enhancement in nanometer-scale ridge aperture antennas. Resent research, including numerical simulations and near field optical measurements has demonstrated that nanoscale ridge antenna apertures can concentrate light into nanometer domain....
-
BNC Annual Research Symposium: Nanoscale Energy Conversion
Online Presentations | 23 Apr 2007 | Contributor(s):: Timothy S Fisher
This presentation is part of a collection of presentations describing the projects, people, and capabilities enhanced by research performed in the Birck Center, and a look at plans for the upcoming year.
-
Planning for Disaster: Designing a Cleanroom to Minimize Risk Should a Disaster Occur
Online Presentations | 09 Apr 2007 | Contributor(s):: John Weaver
The cleanliness levels of a cleanroom or other high-technology facility make it inherently vulnerable to a disaster such as a fire. Historically, even a small event of this type can cause significant downtime and cost millions of dollars in remediation. When designing a cleanroom, steps can be...
-
High-Aspect-Ratio Micromachining of Titanium: Enabling New Functionality and Opportunity in Micromechanical Systems Through Greater Materials Selection
Online Presentations | 09 Apr 2007 | Contributor(s):: Masa Rao
Traditionally, materials selection has been limited in high-aspect-ratio micromechanical applications, due primarily to the predominance of microfabrication processes and infrastructure dedicated to silicon. While silicon has proven to be an excellent material for many of these applications, no...
-
Exploring Electron Transfer with Density Functional Theory
Online Presentations | 11 Jun 2006 | Contributor(s):: Troy Van Voorhis
This talk will highlight several illustrative applications of constrained density functionaltheory (DFT) to electron transfer dynamics in electronic materials. The kinetics of thesereactions are commonly expressed in terms of well known Marcus parameters (drivingforce, reorganization energy and...
-
EDA Challenges in Nanoscale Design: A Synopsys Perspective
Online Presentations | 11 Apr 2006 | Contributor(s):: Rich Goldman
Rich Goldman gives an overview of the current state ofthe semiconductor and EDA (Electronic Design Automation) industry with aspecial focus on the impact of nanometer scale design on design tools andthe economics of the industry.
-
Tutorial on Using Micelle-MD
Online Presentations | 05 Apr 2006 | Contributor(s):: Patrick Chiu, Kunal Shah, Susan Sinnott
This is a tutorial using Micelle-MD. This includes the main capabilities, computation procedure, with format of files generated, and the simulation setup, which includes the material models implemented.
-
Mechanical Properties of Surfactant Aggregates at Water-Solid Interfaces
Online Presentations | 05 Apr 2006 | Contributor(s):: Patrick Chiu, Kunal Shah, Susan Sinnott
This is a talk on the mechanical properties of surfactant aggregates at water-solid interfaces using Micelle-MD. This includes silica indentations of micelles with comparison to experimental data and graphite indentation of Micelle.
-
Thermal Microsystems for On-Chip Thermal Engineering
Online Presentations | 04 Apr 2006 | Contributor(s):: Suresh V. Garimella
Electro-thermal co-design at the micro- and nano-scales is critical for achieving desired performance and reliability in microelectronic circuits. Emerging thermal microsystems technologies for this application area are discussed, with specific examples including a novel micromechanical...