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BME 695N Engineering Nanomedical Systems

BME 695N Lecture 1: Need for New Perspectives on Medicine

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Last 12 Months: updated 01 Sep, 2008
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Contributor(s) James Leary
Purdue University, West Lafayette
Abstract Outline:
  1. The Progression of Medicine
    1. Conventional "modern" medicine
    2. "Personalized" or "molecular" medicine
    3. Nanomedicine "single-cell" medicine
  2. How Conventional Medicine Works for Diagnosis of Disease
    1. Identification of the "diseased state"
    2. Simple measurements of body structure and function
    3. Follow-up clinical tests
    4. Internal examinations by non-invasive in-vivo imaging
    5. Molecular tests for specific gene properties
    6. Comparison of individual results with "normal ranges"
  3. How Conventional Medicine Works for Treatment of Disease
    1. Stabilization of patient – "heal thyself"
    2. Surgical repair of injuries
    3. Treatment with drugs locally
    4. Treatment with drugs systemically
    5. Treatment with targeted therapies
  4. Factors Limiting the Progress of Medicine
    1. Economics
    2. Politics
  5. Some Specific Problems with Conventional Medicine
    1. Consequences of waiting for patient symptoms
    2. Trained people and modern drugs are expensive
    3. Diagnostic technologies, if available, are still relatively primitive and/or expensive
    4. Crude targeting of drugs
  6. Personalized Medicine
    1. Based on genetic characteristics of the individual patient
    2. Specific gene rearrangments or mutations
    3. Specific SNPs (Single Nucleotide Polymorphisms)
  7. Nanomedicine
    1. Medicine performed at single cell level
    2. Possibility of "regenerative medicine"
    3. Blurring of distinction between prevention and treatment
References
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  • Leary, James (2007), "BME 695N Lecture 1: Need for New Perspectives on Medicine," http://www.nanohub.org/resources/3047/.

    BibTex | EndNote

Date posted 03 Aug, 2007
Time 04:30 PM, August 21, 2007
Location Biomedical Engineering Building, Room 1083
Type Online Presentations
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  • 8.8 Ranking Courses Part of: BME 695N Engineering Nanomedical Systems

    BME 695N Engineering Nanomedical Systems

    Type Courses
    Contributor(s) James Leary
    Date 28 Aug, 2007
    Avg. Rating 5.0 out of 5 stars  (1)
    Rate this

    This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell targeting strategies, choice of core nanomaterials, technologies for testing composition and structure …

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