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NCN Nano-Devices for Medicine and Biology: Research Seminars

Potassium Channels: Conduction, Selectivity, Blockage, Inactivation, and Gating

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Contributor(s) Benoit Roux
University of Chicago

NCN SLC@Northwestern
Northwestern University, Evanston
Abstract The determination of the structure of the KcsA K+ channel from Streptomyces lividan has made it possible to investigate the function of a biological channel at the atomic level. Because of its structural similarity with eukaryotic K-channels, investigations of KcsA are expected to help understand a large class of biologically important channels. We are currently working on several fundamental aspects of the function of the KcsA channel such as electrostatics, muti-ion permeation, channel gating, and inhibition by various blocking agents.
Biography Benoit Roux
Professor, Biochemistry & Molecular Biology
University of Chicago
B.Sc. Physics, University of Montreal, 1981
M.Sc. Physics, University of Montreal, 1984
Ph.D. Biophysics, Harvard University, 1990
Sponsored by Northwestern University NCN Student Leadership Council
Network for Computational Nanotechnology
Cite this work

If you reference this work in a publication, please cite as follows:

  • Roux, Benoit; SLC@Northwestern, NCN (2006), "Potassium Channels: Conduction, Selectivity, Blockage, Inactivation, and Gating," http://www.nanohub.org/resources/1959/.

    BibTex | EndNote

Date posted 05 Nov, 2006
Time October 25, 2006
Location Northwestern University, Evanston, IL
Type Online Presentations
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