Description

The Engineered nanoBIO node at Indiana University (IU) develops a powerful set of integrated computational nanotechnology products that address this complex, multiscale problem in both education and research and facilitate the discovery of customized, efficient, and safe nanoscale devices for biological applications. These apps, tools, and frameworks span the range from nanoscale particles (nano) to cellular scale structures (micro) to tissue scale morpohologies (macro).

All Categories (21-40 of 73)

1. CompuCell3D v4 - Bacterium Macrophage simulation

   Tools | 04 Jun 2020 | Contributor(s):: Juliano Ferrari Gianlupi, T.J. Sego

   Macrophage hunts bacterium in a maze

2. CompuCell3D - Simulation of angiogenesis

   Tools | 04 Jun 2020 | Contributor(s):: Juliano Ferrari Gianlupi, T.J. Sego

   CompuCell3D simulates angiogenesis using chemical signals

3. Multiscale Multicellular Modeling of Tissue Function and Disease using CompuCell3D

   Online Presentations | 03 Jun 2020 | Contributor(s):: James A Glazier, Juliano Ferrari Gianlupi

   Multiscale multicellular models combine representations of subcellular biological networks, cell behaviors, tissue level effects and whole body effects to describe tissue outcomes during development, homeostasis and disease. I will briefly introduce these simulation methodologies, the CompuCell3D...

4. COVID 19 Virtual Tissue Model - Tissue Infection and Immune Response Dynamics

   Tools | 26 May 2020 | Contributor(s):: T.J. Sego, Josua Oscar Aponte-Serrano, Juliano Ferrari Gianlupi

   Simulates tissue and immune system interactions during a viral lung infection

5. Shape Changing Nanocontainers Tutorial

   Online Presentations | 22 Apr 2020 | Contributor(s):: Vikram Jadhao

   Course material companion materials for nanoparticle shape lab. Four files are associated with this course material: two video lectures, companion powerpoint slides, and a homework problem set.

6. A virion infected-cell response tissue simulator

   Tools | 13 Apr 2020 | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin

   Simulate infected cell response to virus with PhysiCell

7. A virion replication tissue simulator

   Tools | 13 Apr 2020 | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin

   Simulate virus replication dynamics with PhysiCell

8. A virion endocytosis tissue simulator

   Tools | 13 Apr 2020 | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin

   Simulate virus endocytosis (internalization), ACE2 receptor dynamics with PhysiCell

9. Souffle: Virus Capsid Assembly Lab

   Tools | 01 Apr 2020 | Contributor(s):: Nilsson, Lauren, JCS Kadupitiya, Vikram Jadhao

   Simulate assembly of flexible capsomeres into virus capsids and oligomers

10. PhysiCell model for COVID19

    Tools | 26 Mar 2020 | Contributor(s):: Randy Heiland, Yafei Wang, Paul Macklin

    Prototype 2-D multicellular simulation of COVID19.

11. Mechanics Training App for PhysiCell

    Tools | 14 Feb 2020 | Contributor(s):: Furkan Kurtoglu, Aneequa Sundus, Mishler, Daniel S, Randy Heiland, Paul Macklin

    Training application for "Mechanics" concept in PhysiCell.

12. PhysiCell model with SBML intracellular model

    Tools | 10 Feb 2020 | Contributor(s):: Randy Heiland

    Each cell will have its own intracellular (metabolic) model that will affect the microenvironment.

13. pc4thanos : Thanos vs. Avengers multicellular demonstrator

    Tools | 31 Jan 2020 | Contributor(s):: Paul Macklin

    PhysiCell Thanos vs. Avengers demonstrator for multicellular simulation techniques

14. Overview of the nanoBIO Project

    Series | 28 Jan 2020 | Contributor(s):: Geoffrey C. Fox

    The safe and successful application of nanotechnology in the biological realm is a challenge due to the inherent multiscale nature of biology.Engineering nanoBIO devices requires the knowledge of how nanotechnology-based devices interact with biological systems at the bioenvironment, cell, and...

15. Overview of the nanoBIO Project Part A: General Features and Motivation of Project

    Online Presentations | 28 Jan 2020 | Contributor(s):: Geoffrey C. Fox

16. Overview of the nanoBIO Project Part B: Nano-Micro and Micro Units

    Online Presentations | 28 Jan 2020 | Contributor(s):: Geoffrey C. Fox

17. Overview of the nanoBIO Project Part C: Digital Twins and Engineered Health

    Online Presentations | 28 Jan 2020 | Contributor(s):: Geoffrey C. Fox

18. Overview of the nanoBIO Project Part D: Visualization and Experimental Validation

    Online Presentations | 28 Jan 2020 | Contributor(s):: Geoffrey C. Fox

19. Nanoparticle Shape Lab

    Tools | 10 Jan 2020 | Contributor(s):: JCS Kadupitiya, Nicholas E. Brunk, Vikram Jadhao

    Simulates the low-energy shapes of nanocontainers over a wide range of solution conditions

20. PhysiCell: Extracellular Matrix Modeling

    Tools | 10 Dec 2019 | Contributor(s):: John Metzcar, Ben Duggan, Randy Heiland, Daniel Matthew Murphy, Paul Macklin

    An extracellular matrix model developed in PhysiCell.